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Witnesses are urged to come forward after shooters left 3 dead and 11 wounded in a Philadelphia crowd

A night of revelry on Philadelphia's South Street turned chaotic Saturday as gunmen opened fire into a crowd, leaving three people dead and 11 wounded in one of at least 10 weekend mass shootings across the United States.

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Senate poised to pass first major gun safety legislation in decades following bipartisan agreement

The Senate on Tuesday made meaningful progress toward passing the first major federal gun safety legislation in a generation.

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Twitter launches legal challenge in India over orders to block content

Twitter has mounted its first legal challenge to the Indian government over official orders to take down content.

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People should celebrate the New Year, experts say. But the size and kind of party determine Covid-19 safety

A new year is coming, and it brings along concerns over imminent holiday celebrations in light of the Omicron variant. The coronavirus strain, the latest "variant of concern," according to the World Health Organization, is spreading across the United States quickly. In the next week or 10 days, the virus circulating from holiday gatherings could boost daily numbers to more than half a million, estimates CNN Medical Analyst Dr. Jonathan Reiner, a professor of medicine at George Washington University.

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Explorers say they think they’ve found Amelia Earhart’s long-lost plane

Groundbreaking aviator Amelia Earhart’s tragic and mysterious disappearance while flying over the Pacific Ocean has captivated the world for nearly 87 years, spurring on countless investigations and expeditions for answers on what happened to the beloved pilot.

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About 2% of babies born in US are from IVF - what you need to know

Talk to a group of 100 people born in the United States, and chances are two of them were born as the result of in vitro fertilization, said Dr. Zev Williams, director of the Columbia University Fertility Center.

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Boeing’s stock tumbles after report warns investigation will open ‘new can of worms’

As if Boeing needed any more bad news, a scathing report from Wall Street on Tuesday sent its stock sinking sharply. The report cast doubt on Boeing’s ability to pass a new federal safety audit.

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5 Things for August 22: Afghanistan, Navy Wreck, Barcelona, Baltimore, Secret Service

The Eclipse of the Century is over, but we've got memories to last a lifetime. Here's what else you need to know to Get Up to Speed and Out the Door. (You can also get "5 Things You Need to Know Today" delivered to your inbox daily. Sign up here.)

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5 Things for August 25: Harvey, Samsung Sentence, Execution, Whole Foods

Don't be fooled by the word "energy" in your favorite energy bar. Here's what else you need to know to Get Up to Speed and Out the Door.

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5 Things for Tuesday, June 27: Syria, Health Bill, Travel Ban, Kislyak, Hail

Millennials use public libraries the most, a new report says. Who knew? Here's what else you need to know to Get Up to Speed and Out the Door.

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5 Things for Friday, July 14: Health Care Bill, President Trump, Missing Men, Travel Ban, Overseas Attacks

You're in luck. Today is Pandemonium Day, giving you the perfect excuse to leave the dishes undone and the house a mess. Here's what else you need to know to Get Up to Speed and Out the Door.

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5 Things for Monday, May 8: France, Chibok Girls, Health Care

France has a new president. Learn more about him and everything else you need to know to Get Up to Speed and Out the Door.

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5 Things for Thursday, May 25: Manchester Attack, Russia, Trump, Montana

Manchester's beloved soccer team, Manchester United, won a league title. It was an emotional, bittersweet victory. Here's what else you need to Get Up to Speed and Out the Door.

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5 Things for Friday, April 7: Syria Strikes, Supreme Court, Russia Investigation

President Trump and his Chinese counterpart continue their meetings today in Florida. As you plan your day, here are the 5 things you need to know to Get Up to Speed and Out the Door.

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5 things for March 27: Russia diplomats, Facebook, Kim Jong Un, Census, Linda Brown

Reading by the light of your plants? Yeah, scientists are working on that one. Here's what else you need to know to Get Up to Speed and Out the Door.

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5 things for April 2: China, DACA, Gaza, Teacher walk outs, Sinclair

April's here! That means showers, flowers and...taxes. If you haven't filed yet, hey, there's no shame in needing a little brush-up on how it all works. Here's what else you need to know to Get Up to Speed and Out the Door.

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5 Things for December 18: Atlanta Airport Outage, Tax Overhaul, Russia Investigation

Say hello to Amy Wright, the newest CNN Hero of the Year. Here's what else you need to know to Get Up to Speed and Out the Door.

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5 things for May 1: Russia probe, Uber, N. Korea, Iran-Israel, Cardinal George Pell

The Terrus Museum in southern France has a little bit of a problem. Half of the paintings in its collection are fakes. Here's what else you need to know to Get Up to Speed and Out the Door.

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5 Things for October 27: JFK Files, Niger, Opioids

Which country has the world's most powerful passport? Spoiler alert: it's not the US. Here's what else you need to know to Get Up to Speed and Out the Door.